Evaluation of tilmicosin as a treatment for pneumonia caused by pasteurella multocida in ewes [electronic resource].

Includes references.

Tilmicosin is a semi-synthetic antibiotic used for treatment of respiratory infections in cattle, however, a little is known about the therapeutic use of the drug in sheep. In the present study, fifteen non-pregnant ewes, 2-3 years old with average body weight 40-50 kg. from a private farm at kafr- abohesen,Sharkia province were suffering from broncho- pneumonia caused by pasteurella multocida infection. The diseased ewes were divided into three equal groups, each of 5 animals, and treated with a single subcutaneous dose of tilmicosin at a dose level of 10, 20 and 30 mg/kg. B.wt- respectively.A fourth group of ten apparently healthy, free from Pasteurella multocida infection, non-pregnant ewes of about the same age and weight was served as a control. One week post-treatment with different doses of Tilmicosin, no Pasteurella multocida could be detected in the blood of treated ewes, in addition, the drug was effective in control of broncho- pneumonia and the ewes regained its signs of normal health conditions,-however, the third group which treated with 30 mg/kg. B.wt. was depressed, move slowly with reduced

Summary in Arabic.

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