Sero-epidemiological study on caprine arthritis-encephalitis virus infection in goats in two localities in Egypt [electronic reource].

By: Contributor(s): Language: English Summary language: Arabic Description: p. 68-78Uniform titles:
  • Alexandria journal of veterinary science, 2018 v. 59 (1) [electronic reource].
Online resources: In: Alexandria Journal of Veterinary Science 2018.v.59(1)Summary: Caprine Arthritis Encephalitis (CAE) is a chronic viral disease of domestic goats caused by a member of lentivirus of the family Retroviridae. In this study, the prevalence of caprine arthritis encephalitis virus in two governorates in Egypt was investigated. A total of 176 serum samples were collected from local (Egyptian Nubian, Egyptian Baladi which is the native breed) and foreign breeds (Barki and Shami) of goats from ten flocks from different localities in Behera and Alexandria governorates. Enzyme-linked-immuno-sorbent assay (ELISA) was employed for detection of anti –p28 antibodies directed against CAEV. Sero prevalence on the herd level was 30% (3/10 herds were positive). Sero prevalence on the individual level was 8.52%. All sero positive animals were from the breed Barki (15/106) at a percentage of 14.15%. Higher percentages of positive animals were recorded in females and at age between 4-5 years. All serologically positive cases (15) were in animals raised by open system (132), at a percentage of 11.36%. There was 100% correlation between the results of ELISA test in caprine serum and milk whey samples. In conclusion: The best of our knowledge this is the first study recorded the presence of caprine arthritis encephalitis in Egypt and further study to characterize the virus and wider seroprevalence study is required. The Milk whey ELISA test proved to be accurate simple non-invasive technique for surveillance of the disease on herd bases.
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Includes references.

Caprine Arthritis Encephalitis (CAE) is a chronic viral disease of domestic goats caused by a member of lentivirus of the family Retroviridae.
In this study, the prevalence of caprine arthritis encephalitis virus in two governorates in Egypt was investigated. A total of 176 serum samples
were collected from local (Egyptian Nubian, Egyptian Baladi which is the native breed) and foreign breeds (Barki and Shami) of goats from ten flocks
from different localities in Behera and Alexandria governorates. Enzyme-linked-immuno-sorbent assay (ELISA) was employed for detection of
anti –p28 antibodies directed against CAEV. Sero prevalence on the herd level was 30% (3/10 herds were positive). Sero prevalence on the individual
level was 8.52%. All sero positive animals were from the breed Barki (15/106) at a percentage of 14.15%. Higher percentages of positive animals
were recorded in females and at age between 4-5 years. All serologically positive cases (15) were in animals raised by open system (132), at a
percentage of 11.36%. There was 100% correlation between the results of ELISA test in caprine serum and milk whey samples. In conclusion: The best
of our knowledge this is the first study recorded the presence of caprine arthritis encephalitis in Egypt and further study to characterize the virus
and wider seroprevalence study is required. The Milk whey ELISA test proved to be accurate simple non-invasive technique for surveillance of the disease
on herd bases.

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