Biochemical characterization of Arabidopsis thaliana DNA polymerase λ (Record no. 41945)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01970cab a2200325Ia 45 0 |
| 001 - CONTROL NUMBER | |
| control field | u186838 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | SIRSI |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 101106s2009 ua ss b eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EAL |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | ART JGEB V7 No2 3 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amoroso, Alessandra. |
| 240 10 - UNIFORM TITLE | |
| Uniform title | Journal of genetic engineering and biotechnology, 2009.v. 7 (2) |
| Medium | [electronic resource]. |
| 245 10 - TITLE STATEMENT | |
| Title | Biochemical characterization of Arabidopsis thaliana DNA polymerase λ |
| Medium | [electronic resource]: |
| Remainder of title | role in the oxidative DNA damage bypass. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p.11-16. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | As obliged phototropic organisms, plants are continuously exposed to high level of reactive oxygen ,species (ROS), generated within the ceII as a result of the exposure to biotic stresses. sunlight and metabolic activity. The most frequent DNA oxidation damage. generated by ROS is the 7,8-dihydro-8 oxo-guanine (8-oxo-G) adduct, When present in the replicating DNA strand, this lesion is highly mutagenic, leading to the insertion by the replicative DNA polymerases (pols) of an adenine in place of the correct cytosine. Here we present the first characterization of an error-free mechanism for 8-oxo-G bypass operating in crude extracts of Arabidopsis thaliana. For the first time, our results show that, similarly to what observed in mammalian cells. plant cells prossess an efficient pathway for faithful translesion synthesis of oxidative DNA lesions. |
| 596 ## - | |
| -- | 1 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Arabidopsis thaliana. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA polymerases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA damage. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oxidative stress. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic translation. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Conica, Lorenzo. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Longoni, Paolo. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Crespan, Emmanuele. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cella, Rino. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maga, Giovanni. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of Genetic Engineering and Biotechnology. |
| Related parts | 2009.v.7(2) |
| International Standard Serial Number | 1687-157X |
| Control subfield | nnas |
| Record control number | u186667 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nile.enal.sci.eg/EALE/2009/JGEB/709/2/11.pdf">http://nile.enal.sci.eg/EALE/2009/JGEB/709/2/11.pdf</a> |
| Public note | Full Text Article. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Articles |
| Source of classification or shelving scheme | Library of Congress Classification |
No items available.