The protective role of folic acid, vitamin B12 and vitamin C on the mutagenicity of the anticancer drug ifosfamide (Record no. 41964)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01542cab a2200301Ia 45 0 |
| 001 - CONTROL NUMBER | |
| control field | u186857 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | SIRSI |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 101107s2009 ua ss b eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EAL |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | ART JGEB V7 No2 7 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Donya, Souria M. |
| 240 10 - UNIFORM TITLE | |
| Uniform title | Journal of genetic engineering and biotechnology, 2009.v. 7 (2) |
| Medium | [electronic resource]. |
| 245 14 - TITLE STATEMENT | |
| Title | The protective role of folic acid, vitamin B12 and vitamin C on the mutagenicity of the anticancer drug ifosfamide |
| Medium | [electronic resource]. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p.41-50. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Ifosfamide (Holoxan, IFO) is an oxazaphospoorine alkylating agent with a broad spectrum of antineoplastic activity. IFO can damage DNA during any phase of the celI cycle and therefore, is not phase-specific. Thus the objective of this investigation is to measure the potential cytotoxicity of IFO alone and in combination with vitamins (FA, VB12 and VC) The genotoxic potential of IFO was evaluated in vivo using different mutagenic end points. |
| 596 ## - | |
| -- | 1 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Folic acid |
| General subdivision | Physiological effect. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Vitamin B12 |
| General subdivision | Physiological effect. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Vitamin C |
| General subdivision | Physiological effect. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA damage. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic agents. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cancer |
| General subdivision | Treatment. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aly, Fawzia A. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abo-Zeid, Mona A. M. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of Genetic Engineering and Biotechnology. |
| Related parts | 2009.v.7(2) |
| International Standard Serial Number | 1687-157X |
| Control subfield | nnas |
| Record control number | u186667 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nile.enal.sci.eg/EALE/2009/JGEB/709/2/41.pdf">http://nile.enal.sci.eg/EALE/2009/JGEB/709/2/41.pdf</a> |
| Public note | Full Text Article. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Articles |
| Source of classification or shelving scheme | Library of Congress Classification |
No items available.