MARC details
| 000 -LEADER |
|---|
| fixed length control field |
cab a22 a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
u193882 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
ENAL |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
170407s2017 ua ss b eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EAL |
| Transcribing agency |
EAL |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract |
ara |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
ART ASEJ V38 No1 10 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Hamed, Nadia A. |
| 9 (RLIN) |
24956 |
| 240 10 - UNIFORM TITLE |
|---|
| Uniform title |
Alexandria science exchange journal, 2017 v. 38 (1) |
| Medium |
[electronic resource]: |
| 245 10 - TITLE STATEMENT |
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| Title |
Protective effect of quercetin against oxidative Stress and mitochondrial bioenergetic deficiency caused by lambda- cyhalothrin |
| Medium |
[electronic resource] |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
التأثير الوقائى للكيرسيتين ضد الاكسدة و نقص الطاقة البيولوجية فى الميتوكوندريا التى يسببها لامبادا سيهالوثرين |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
P. 83-88 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes references. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Mitochondria are a convenient model to understand the oxidative damage induced by various xenobioticprooxidants. This study was designed to investigate (1) the possibility of lambda-cyhalothrin (LCT), a type II pyrethroid, to induce oxidative stress response in rabbit liver mitochondria in vitro and its effect on selected parameters and (2) the role of quercetin in alleviating the cytotoxic effects of LCT. Mitochondria were divided into two groups. The first group, mitochondria were incubated for 30 min at 37oC with different concentrations (0, 5, 10, 15 and 20uM) of LCT. In the second group, mitochondria were pre-incubated with (10µM) quercetin for 30 min and followed by LCT incubation for 30 min at 37oC. Following in vitro exposure, LCT caused a significant induction of oxidative damage in mitochondria at all tested concentrations as evidenced by increased superoxide dismutase (SOD) activity and reduced glutathione (GSH) level. However, a significant decrease in the activities of NADH dehydrogenase and ATP synthase (ATPase) was obtained. While the quercetin treated mitochondria showed significant enhancement in all tested parameters except GSH content, there was no significant change. Quercetin showed a significant protection against the cytotoxic effects induced by LCT on the studied parameters. In conclusion, antioxidant quercetin could be able to ameliorate LCT-induced oxidative stress by altering antioxidant defense system and recovered the bioenergetic activity of mitochondria. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
Summary in Arabic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Quercetin |
| 9 (RLIN) |
24957 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Oxidative stress |
| 9 (RLIN) |
1489 |
| 650 #3 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
lambda-cyhalothrin |
| 9 (RLIN) |
24958 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Bioenergetics |
| 9 (RLIN) |
13993 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
24941 |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Alexandria Science Exchange Journal. |
| Related parts |
2017.v.38(1) |
| International Standard Serial Number |
1110-0176 |
| Control subfield |
nnas |
| Record control number |
u193445 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://nile.enal.sci.eg/EALE/2017/ASEJ/3817/1/82.pdf |
| Public note |
Full Text Article |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Articles |
AR |
| Source of classification or shelving scheme |
alc |