Physiological effects of perinatal stress on hypothalamic-pituitary-adrenal (HPA) axis in rat pups with model of hyperthyroidal mothers (Record no. 64181)
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| 000 -LEADER | |
|---|---|
| fixed length control field | nab a22 7a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 300419s2019 au ||||ssb||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EAL |
| Transcribing agency | EAL |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | ara |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | ART AVMJ V60 No160 17 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sotohy, Sotohy A. |
| 9 (RLIN) | 844 |
| 240 10 - UNIFORM TITLE | |
| Uniform title | Assiut veterinary medical journal, 2019 v. 65 (160) |
| Medium | [electronic resource] |
| 245 10 - TITLE STATEMENT | |
| Title | Physiological effects of perinatal stress on hypothalamic-pituitary-adrenal (HPA) axis in rat pups with model of hyperthyroidal mothers |
| Medium | [electronic resource] |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التأثيرات الفسيولوجية للتعرض للاجهاد حول الولادة على محور الاجهاد العصبى الهرمونى فى صغار الجرذان لأمهات مصابة بمرض زيادة افرازات الغدة الدرقية |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p. 142-150. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographic reference. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hyperthyroidism is common endocrine problem encountered in pregnancy. It is well known that hyperthyroidism induces an increase in the activity of hypothalamic- pituitary – adrenal (HPA) axis. There are a few reports about development of the HPA axis in rat pups of hyperthyroid mothers. Therefore, this study was designed to investigate that maternal hyperthyroidism during pregnancy impaired feedback mechanisms of the HPA- axis and associated with thyroid disorders and neurobiological alterations in off sprigs. Therefore, 30 female wistar rats (200-250gm) after induction of pregnancy and hyperthyroxinemia. Their pups were divided into six groups (control non stressed group, hyperthyroid non stressed group, treated non stressed group, control stressed group, hyperthyroid stressed group, treated stressed group). Measurement of some hormones and histological analyses were done and result the induction of hyperthyroidism in mothers was significantly increased of plasma T4 and decreased of plasma TSH levels in all pups group compared with control group. ACTH and Corticosterone increased in stressed group compared with other group. In addition hyperthyroid group showed small amount of colloid with irregular structure and architecture of the thyroid gland compared with treated and control group. In conclusion, the effects of maternal stress exposure during pregnancy on HPA-axis regulation and anxiety-like behavior can be transferred via the maternal line to the its off spring's. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Summary in Arabic |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdel-sater, khaled A. |
| 9 (RLIN) | 25240 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud, Mohamed A. |
| 9 (RLIN) | 25241 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud, Mahmoud Abd-Elkareem |
| 9 (RLIN) | 25242 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdel-kareem, Asmaa H. |
| 9 (RLIN) | 25243 |
| 773 0# - HOST ITEM ENTRY | |
| Title | Assiut Veterinary Medical Journal |
| Related parts | 2019.v.65(160) |
| International Standard Serial Number | 1012-5973 |
| Control subfield | nnas |
| Record control number | u181356 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://nile.enal.sci.eg/EALE/2019/AVMJ/6519/160/142.pdf |
| Public note | Full Text Article |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | alc |
| Articles | AR |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Total Checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alphabetical Classification | Main | Main | 04/30/2019 | ART AVMJ V60 NO160 17 | 04/30/2019 | 04/30/2019 | Articles |