Pharmacological studies on some antibacterial agents in fish [electronic resource].
دراسات فارماكولوجية على بعض مضادات الميكروبات فى الاسماك.
- p.87-94.
Includes references.
The antibacterial activities of amoxicillin and florfenicol were investigated both in-vitro and in-vivo against Aeromonas hydrophila in Clarias Lazera . The obtained results indicated that the two drugs were effective in vitro against microorganism. The antibacterial activity of these drugs in their therapeutic doses decreased the mortality rate (%) and pathogenic clinical signs compared to that of infected non medicated group. The estimated hematological parameters showed that both amoxicillin and florfenicol caused a slight decrease in RBCs, WBCs counts, Hb, and PCV % and all these changes were reversible and returned back to the normal range within 7 days post treatment . The effects of these drugs on the estimated bJochemical parameters showed that, amoxicillin and florfenicol induced non significant changes in the most of biochemical parameters (AST, urea and creatinine) compared to the control group. While significant changes were recorded between amoxicillin and florfenicol treated group and that infected non treated one.