TY  - SER
AU  - Zaki,Mona S.
AU  - Mohamed,M.I.
AU  - Nasr,Soad M.
AU  - El-Kady,R.M.
AU  - El-Belbasi,H.I.
TI  - Protective effect of antidote against free radicals induced by aflatoxin B1 in lambs
KW  - Lambs
KW  - Diseases
KW  - Aflatoxins
KW  - Physiological effect
KW  - Liver function tests
KW  - Kidney function tests
KW  - Trace elements in animal nutrition
N1  - Includes references
N2  - Aflatoxin B1 is a potent hepatotoxic and hepatocarcinogenic mycotoxin produces oxidative damage to the tissues through lipid peroxidation. A high morbidity and mortality were recorded in a lambs farm in a village belonging to Mounofia Governorate, 10 out of 40 balady lambs were moribund showing diarrhoea, salivation, caugh, sneezing with mucopurulent discharge and dyspenea. The Post-mortem examination revealed' intestinal congestion with hemorrhagic spots, flabby heart with hydropericardium and enlarged congested liver and kidneys. There was a significant increase in liver enzymes, urea, creatinine and magnesium. There was significant decrease in digestibility and daily body weight gain in lambs suffered from aflatoxicosis. After treatment with the antidote for 7 days, all parameters returned to normal. Determination of aflatoxin in ration of corn revealed the presence of aflatoxin B 1. Additional keyword: Lambs - aflatoxin B1-antidote - serum biochemistry- liver function kidney function- minerals -- trace elements digestibility
UR  - http://nile.enal.sci.eg/EALE/2004/BSVMJ/1404/1/1.pdf
ER  -