Normal view MARC view ISBD view

Pharmacological profile of some cytochrome P 450 modulators [electronic resource]: 1. Effect on some steroidal hormones.

By:

Abdel-Aziz, Sayed A

Contributor(s):

Language: English Summary language: Arabic Description: p.113-123Other title:

الصورة الفارماكولوجية لبعض محورات أنزيم السيتوكروم ب 450 1- التأثير على بعض الهرمونات الاستيرودية.‪ [Added title page title]

Uniform titles:

Zagazig veterinary journal, 2011 v. 39 (3) [electronic resource].

Subject(s):

Online resources:

Full Text Article.

In: Zagazig Veterinary Journal 2011.v.39(3)Summary: The present study was carried out to study the effect of ciprofloxacin (CYP-450 inhibitor) and rifampicin (CYP-450 inducer) on some endogenous steroidal hormones (estradiol, progesterone, testosterone and cortisol) and exogenously administered progesterone and testosterone hormones in mature male & female rats. Ninety mature male and female rats were divided into 9 equal groups (each of 5 males and 5 females). The first group was left without treatment and kept as normal control group. The second group was given ciprofloxacin in a dose of 1.8 mg/100 gm. B.wt. i.p daily for 5 days. The third group received rifampicin (2.25 mg/100 gm) i.p for 5 successive days, the 4th group received testosterone 2.5 mg/100 gm) given as a single s.c dose 24 hours before blood sampling and served as testosterone control group,

Average rating: 0.0 (0 votes)

No physical items for this record

Includes references.

The present study was carried out to study the effect of ciprofloxacin (CYP-450 inhibitor) and rifampicin (CYP-450 inducer) on some endogenous steroidal hormones (estradiol, progesterone, testosterone and cortisol) and exogenously administered progesterone and testosterone hormones in mature male & female rats. Ninety mature male and female rats were divided into 9 equal groups (each of 5 males and 5 females). The first group was left without treatment and kept as normal control group. The second group was given ciprofloxacin in a dose of 1.8 mg/100 gm. B.wt. i.p daily for 5 days. The third group received rifampicin (2.25 mg/100 gm) i.p for 5 successive days, the 4th group received testosterone 2.5 mg/100 gm) given as a single s.c dose 24 hours before blood sampling and served as testosterone control group,

Summary in Arabic.

There are no comments on this title.

to post a comment.