000 02318cab a2200325Ia 45 0
001 u190100
003 SIRSI
008 110308s2007 ua ss b eng d
040 _aEAL
041 _aeng
_bara
090 _aART ZVJ V35 No4 10
100 1 _aEdrees, Nariman M. M.
240 1 0 _aZagazig veterinary journal, 2007 v. 35 (4)
_h[electronic resource].
245 1 0 _aClinicopathological and toxocological studies on the effect of vanadium pentoxide as anticarcinogenic
_h[electronic resource].
246 1 5 _aدراسات باثولوجية إكلينيكية على تأثير خامس أكسيد الفاناديوم كمضاد للسرطان.
300 _ap.75-87.
504 _aIncludes references.
520 _aVanadium (V) is a heavy metal and trace element. It is believed to be a novel anticarcinogenic agent. It helps in the protection against the cancer induced by dimethylbenzantheracene (DMBA), adenocarcinoma in female-albino rats. One hundred and five female rats were divided into four gps. Gp.(I), 15 rats, was the negative control. Gp.(2), 30 rats, was orally intubated by vanadium pentoxide (0.05mglkg B.wt for 150 days), Gp.(3), 30 rats, was orally given DMBA(lOOmglkg B.wt, the dose was divided into 4 weekly applications, dissolved in corn oil.. Gp.(4) , 30 rats, was orally given vanadium (0.05mglkg B.wt for 150 days). Four weekly oral doses of DMBA, dissolved in corn oil were given after one month from the start of vanadium which continued for 150 days. Blood samples were collected from the retroorbital venous plexus for hematological and biochemical studies after 90, 120 and 150 days from the beginning of the experiment. Specimens were taken at the same time from the liver, kidneys, lungs, spleen, mammary glands, oviduct and ovaries for histopathological examination after sacrifice of the rats.
546 _aSummary in Arabic.
650 0 _aCancer
_xTreatment.
650 0 _aCancer
_xResearch.
650 0 _aVanadium
_xPhysiological effect.
650 0 _aVanadium
_xTherapeutic use.
650 0 _aVanadium
_xToxicology.
700 1 _aIbrahim, Khlood M.
700 1 _aEldin, Dina M.
773 0 _tZagazig Veterinary Journal.
_g2007.v.35(4)
_x1110-1458
_7nnas
_wu189860
856 4 0 _uhttp://nile.enal.sci.eg/EALE/2007/ZVJ/3507/4/75.pdf
_zFull Text Article
596 _a1
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_2lcc
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