000 01747cab a2200289Ia 45 0
001 u203056
003 SIRSI
008 121108s2011 ua ss b eng d
040 _aEAL
041 _aengbara
090 _aART ZVJ V39 NO3 18
100 1 _aMohmad, M. A.
240 1 0 _aZagazig veterinary journal, 2011 v. 39 (3)
_h[electronic resource].
245 1 0 _aPharmacokinetic evaluation of cefotaxime after intramuscular administration in chickens
_h[electronic resource].
246 1 5 _aتقييم الحركة الدوائية للسيفوتاكسيم بعد الحقن العضلى فى الدجاج.‪
300 _ap.155-159.
504 _aIncludes references.
520 _aPhannacokinetics of cefotaxime was investigated in clinically healthy chickens following single intramuscular injection of three doses (5, 10 and 20 mglkg.bwt.). An increase in concentration of the drug was found with increasing dose at all the sampling times in each subject. The peak serum concentrations (Cmax) of cefotaxime was 4.5, 8.0 and 21.60Jlglml at maximum time at which the drug reach maximum concentration (tmax) of 28, 29 and 30 minutes, respectively. The serum concentrations was decreased with elimination half lives (lO.5e) of 0.72 ,0.70 and 0.71 hours and The area under serum drug concentration (AUCo-oo) was 7.09, 12.32 and 32.58 Jlg.mP.h for the three doses, respectively.
546 _aSummary in Arabic.
650 0 _aPharmacokinetics.
650 0 _aCefotaxime
_xPharmacokinetics
650 0 _aEscherichia coli infections.
700 1 _aGehan, NA
773 0 _tZagazig Veterinary Journal.
_g2011.v.39(3)
_x1110-1458
_7nass
_wu189860
856 4 0 _uhttp://nile.enal.sci.eg/EALE/2011/ZVJ/3911/3/155.pdf
_zFull Text Article.
596 _a1
942 _cAR
_2lcc
999 _c54858
_d54858