Protective immunity aganist brucella infection following immunization with periplasmic proteins of brucella melitensis (Record no. 44908)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02870cab a2200313Ia 45 0 |
| 001 - CONTROL NUMBER | |
| control field | u190326 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | SIRSI |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 110316s2008 ua ss b eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EAL |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | ara |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | ART AVMJ V54 No117 13 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Zaki, Hoda M. |
| 9 (RLIN) | 2530 |
| 240 10 - UNIFORM TITLE | |
| Uniform title | Assiut veterinary medical journal, 2008 v. 54 (117) |
| Medium | [electronic resource]. |
| 245 10 - TITLE STATEMENT | |
| Title | Protective immunity aganist brucella infection following immunization with periplasmic proteins of brucella melitensis |
| Medium | [electronic resource]. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | المناعة الواقية ضد العدوى بالبروسيلا بعد التحصين بالبروتين البريبلازمى للبروسيلا ميلتنسس. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p.169-189. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In this study the humoral and cell mediated immune responses and protective effect induced in BALB/C mice immunized with Brucella melitensis periplasmic proteins precipitated with ammonium sulphate at 50% saturation (BCSP₇₀) or precipitated with ammonium sulphate 70% saturation (BCSP₇₀) were evaluated. Serological results of an enzyme linked immunosorbent assay (ELISA) indicated that the immunoglobulin G increased as a response to inoculation of these antigens. Lymphocyte proliferation (LP) and delayed type hypersensitivity (DTH) also increased due to immunization with BCSP₇₀ and BCSP₅₀. However, immunization of mice with BCSP₇₀ and BCSP₅₀ suppressed splenic infection resulting in reduction in the numbers of CFU per spleen compared to non immunized controls. Overall results suggested that BCSP₅₀ was more effective in inducing protective immunity to Brucella meltlensis biovar3 infection thanBCSP₇₀. Histopathological examination of mice of group (1) revealed deplesion of white pulp and proliferation of reticuloendothelial cells in spleen, activation of kupffer cells with degenerative changes in hepatocytes and granulomatous reaction in liver, interstitial pneumonia and hyperplastic proliferation of bronchial epithelium in lung, degenerative changes of renal tubules and hypercellularity of glomeruli. While group II and III which were immunized either by BCSP₇₀ or BCSP₅₀ revealed lesions in all specimens were of much moderate nature indicating the protective effect of them against Brucella melitensis with attention that the later has more protective effect. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Summary in Arabic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brucellosis |
| General subdivision | Immunological aspects. |
| 9 (RLIN) | 379 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brucella melitensis. |
| 9 (RLIN) | 997 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Periplasmic Proteins. |
| 9 (RLIN) | 3604 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brucellosis vaccines. |
| 9 (RLIN) | 379 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice as laboratory animals. |
| 9 (RLIN) | 331 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yehya, Manal M. |
| 9 (RLIN) | 3605 |
| 773 0# - HOST ITEM ENTRY | |
| Title | Assiut Veterinary Medical Journal. |
| Related parts | 2008.v.54(117) |
| International Standard Serial Number | 1012-5973 |
| Control subfield | nnas |
| Record control number | u181356 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nile.enal.sci.eg/EALE/2008/AVMJ/5408/117/169.pdf">http://nile.enal.sci.eg/EALE/2008/AVMJ/5408/117/169.pdf</a> |
| Public note | Full Text Article. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Articles |
| Source of classification or shelving scheme | Library of Congress Classification |
No items available.