Evaluation of bean seeds and pomegranate fruit fractions as hypocholesterolemic and hpolipidemic agents in albino rats (Record no. 49718)

MARC details
000 -LEADER
fixed length control field 04460cab a2200337Ia 45 0
001 - CONTROL NUMBER
control field u196659
003 - CONTROL NUMBER IDENTIFIER
control field SIRSI
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100414s2009 ua ss b eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EAL
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
Language code of summary or abstract ara
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) ART JBCES V4 No3 I 15
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Abdel-Rahim, Emam Abdel-Mobdee.
240 10 - UNIFORM TITLE
Uniform title Journal of biological chemistry and environmental sciences, 2009 v. 4 (3)
Number of part/section of a work Part 1
Medium [electronic resource].
245 10 - TITLE STATEMENT
Title Evaluation of bean seeds and pomegranate fruit fractions as hypocholesterolemic and hpolipidemic agents in albino rats
Medium [electronic resource].
246 15 - VARYING FORM OF TITLE
Title proper/short title تقييم بذور الفاصوليا و مكونات ثمار الرمان كعوامل خافظة للكولسترول و ليبيدات الدم في الفئران البيضاء.‪
300 ## - PHYSICAL DESCRIPTION
Extent p.239-260.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Includes reference.
520 ## - SUMMARY, ETC.
Summary, etc. The present study was undertaken to evaluate the influences of soaked white bean seeds and pomegranate fractions (seeds and peels) on lipid profiles of rats suffering from hyperlipidemia and hypercholesterolemia. The investigation was based on that legume and fruits as good hypolipidemic and hypocholesterolemic agents which contain protein and appreciable amount of phenols that are known to possess lipotropic and antioxidant characters. The lipotropic and antioxidant power of protein and phenols are supposed to protect blood lipid fractions from oxidation and precipitations on the walls of the blood vessel thus alleviated atherosclerosis. The study was done on soaked bean seeds, pomegranate seeds and dried pomegranate peels and their mixture to evaluate them as hypolipidemic agents by rats feeding to clarify whether the effect is attributed to whole dried seeds and peels. The three present hypolipidemic agents individually and their mixture (1:1:1) amounted 10% of the basal diet. Chemical composition of dried soaked bean and pomegranate (seeds and peels) was determined on dry matter which amounted good values of protein, lipids, crude fiber and phenols. Also, HPLC analysis of pomegranate seeds and peels for the phenols content showed the present of about 16 compounds varying in amount between them. It was noticed that compounds such as catechin and phenol are dominating and daidzin, genistein, cinnamic acid, kaempferol, eugenol, chrysin and galangin were detected in the both pomegranate fractions. The present study showed that the treatments with bean seeds, pomegranate (seeds or peels) and specially their mixture can effect as hypolipidemic and hypocholesterolemic agents and improved the fractions of liver and kidneys as well as lipid peroxidation and the activity of antioxidative enzymes (SOD and catalase) but these treatments had insignificant effects on blood glucose of the hyperlipidemic and hypolipidemic rats. The obtained results showed a good hypolipidemic powerful for soaked bean seeds and pomegranate (seeds and peels) as well as their mixture. Bean seeds diet produced a general improvement in the clinical status of blood lipid profile (total lipids, triglycerides, cholesterol, HDL-c, LDL-c and VLDL-c), liver function (GOT, GPT and bilirubin), kidneys function (uric acid, urea and creatinine) and blood lipid peroxidation and antioxidant enzymes (SOD and catalase) by which hyperlipidemia and hypercholesterolemia were reduced. The mixture diet had the best influence concerning biological studies than the other treatments which used bean seeds and pomegranate (seeds or peels) alone. From the present results the anticholesterolemic and antilipidemic power of the different diet treatments can be arranged in the following from increasing to decreasing order: Mixture ≥ Soaked bean seeds > Pomegranate seeds ≥ Pomegranate peels Future studies are required to evaluate the interaction between lipotropic factor (protein) and antioxidative agent (phenols) which produced such synergetic effects.
546 ## - LANGUAGE NOTE
Language note Summary in Arabic.
596 ## -
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650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Peas
General subdivision Composition
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pomegranate
General subdivision Composition
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hypochondria.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rats
General subdivision Feeding and feeds
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Romeilah, Ramy Mohammed.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gabr, Farouk Abdel-Hameid.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Alam, Sahar Osman.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ali, Haytham Emad El-Dien.
773 0# - HOST ITEM ENTRY
Title Journal of Biological Chemistry and Environmental Sciences.
Related parts 2009.v.4(3)I
International Standard Serial Number 1687-5478
Control subfield nnas
Record control number u159296
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://nile.enal.sci.eg/EALE/2009/JBCES/409/3/part I/239.pdf">http://nile.enal.sci.eg/EALE/2009/JBCES/409/3/part I/239.pdf</a>
Public note Full Text Article.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Articles
Source of classification or shelving scheme Library of Congress Classification

No items available.


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