Effect of different doses of sodium ortho vandate supplementation on DNA and sialic acid in rats (Record no. 50867)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03001cab a2200325Ia 45 0 |
| 001 - CONTROL NUMBER | |
| control field | u197954 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | SIRSI |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 110403s2011 ua ss b eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EAL |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | ara |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | ART SCVMJ V16 No1 14 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ibrahim, A. L. |
| 240 10 - UNIFORM TITLE | |
| Uniform title | Suez canal Veterinary medicine journal, 2011 v. XVI (1) |
| Medium | [electronic resource]. |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of different doses of sodium ortho vandate supplementation on DNA and sialic acid in rats |
| Medium | [electronic resource]. |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير الجرعات المختلفة من الصوديوم أورثو فاندات على الحمض النووى الداى أوكسي الريبوزى و حمض الساليك في الفئران. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | p.121-128. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study was conducted to investigate the biochemical effect of low and high doses of sodium ortho- vandate supplementation on some blood and organ parameters in rats. The experimental study was carried out on 63 adult male rats weighing 150-200 gm. Rats were randomly divided into three equal groups each one comprised 21 rats and classified as follow: Group I (control group), group II (low dose of sodium ortho-vanadate group received 0.2 mg/ml sodium chloride solution 80 roM) and group III (high dose of sodium ortho-vanadate group received 0.6 mg/ml sodium chloride solution 80 mM) via drinking water. Blood samples and tissue specimens were collected after 2, 4 and 6 weeks from the onset of sodium ortho-vanadate supplementation. The obtained results revealed that a reduction (p< 0.05) in serum total sialic acid (TSA) concentration and the percentage of liver DNA fragmentation were observed after 4 and 6 weeks of low dose of sodium ortho-vanadate, 0.2 mg/ml (VLD) administration as compared with control. Meanwhile a marked increase (p< 0.05) in TSA and percentage of liver, heart DNA fragmentation were recorded after administration of sodium ortho vandate at high dose, 0.6 mg/ml (VHD) al1 over the period of the experiment. In addition, an elevation in heart and liver DNA content and reduction in the percentage of heart DNA fragmentation were observed after 6 weeks in VLD- treated group. From the obtained results it could be concluded that, low dose of sodium ortho-vanadate has antioxidant and antiapoptotic effect, while high dose of sodium ortho-vanadate has prooxidant and apoptotic effect. Key words: sodium ortho-vanadate, dose, oxidative stress, DNA, sialic acid, rats. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Summary in Arabic. |
| 596 ## - | |
| -- | 1 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sialic acids |
| General subdivision | Physiological effect. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animal models in research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA damage. |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | sodium orthophenylphenoxide |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | El-Ghannam, A. A. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shalaby, Abeer A. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bahr, Hoda I. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Suez canal Veterinary Medicine Journal. |
| Related parts | 2011.V.XVI(1) |
| International Standard Serial Number | 1110-6298 |
| Control subfield | nnas |
| Record control number | u190916 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://nile.enal.sci.eg/EALE/2011/SCVMJ/1611/1/121.pdf">http://nile.enal.sci.eg/EALE/2011/SCVMJ/1611/1/121.pdf</a> |
| Public note | Full Text Article. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Articles |
| Source of classification or shelving scheme | Library of Congress Classification |
No items available.