MARC details
| 000 -LEADER |
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| fixed length control field |
02936nab a22003137a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
210224s2019 ua gr|psq|||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
EAL |
| Transcribing agency |
EAL |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract |
ara |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
ART EJZ V71 JUN 6 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
El-Bagoury, Adel A. |
| 240 10 - UNIFORM TITLE |
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| Uniform title |
Egyptian journal of zoology |
| Medium |
[electronic resource] |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Effects of virgin coconut oil and lauric acid “with or without 5-fluorouracil” on dimethylhydrazine-induced hepatotoxicity in male rats |
| Medium |
[electronic resource] |
| 246 15 - VARYING FORM OF TITLE |
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| Title proper/short title |
تأثيرات زيت جوز الهند البكر وحمض اللوريك"فى وجود أو غياب 5-فلورويوراسيل" علي السمية الكبدية المستحثة بثنائي ميثيل الهيدرازين في ذكور الجرذان. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
p. 56-69 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographic reference |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Dimethylhydrazine (DMH) is highly toxic for the different body organs, including the liver. The current study aimed to investigate the potential <br/>protective role of virgin coconut oil (VCO) and lauric acid (LA) in presence/absence of a chemotherapy drug “5-fluorouracil (5-FU)” against the <br/>hepatoxicity induced by DMH in male rats (Rattus norvegicus). Ninety rats were randomly divided into nine groups (n = 10). (G1) control group; <br/>(G2) rats received 4 mL VCO/kg body weight (b.wt) , orally/day after day for six weeks starting from week 13; (G3) rats received LA (200 mg/kg b.wt), <br/>orally/day after day for six weeks as in G2; (G4) rats were injected subcutaneously (s.c.) with DMH (20 mg/kg b.wt), once/week for the first six weeks; <br/>(G5) rats received DMH as in G4 and intraperitoneally (i.p.) injected with 5-FU (75 mg/kg b.wt), once/week starting from week 13 for three successive weeks; <br/>(G6) rats received DMH and VCO as in G4 and G2, respectively; (G7) rats received DMH and LA as in G4 and G3, respectively; (G8) rats received DMH, 5-FU, <br/>and VCO as in G4, G5, and G2, respectively; (G9) rats received DMH, 5-FU, and LA as in G4, G5, and G3, respectively. The results showed that DMH injection <br/>caused oxidative stress and histopathological alterations in the liver tissue, as well as dyslipidaemia. However, treatment of male rats with VCO or LA in <br/>presence/absence of 5-FU reduced significantly the DMH-induced hepatotoxicity.<br/>Keywords: 5-Fluorouracil-Dimethylhydrazine-Hepatotoxicity-Lauric acid-Virgin coconut oil<br/><br/> |
| 546 ## - LANGUAGE NOTE |
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| Language note |
Summary in Arabic |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Fluorouracil |
| General subdivision |
Physiological effect. |
| 9 (RLIN) |
33072 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Dimethylhydrazine. |
| 9 (RLIN) |
33048 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Hepatotoxicology. |
| 9 (RLIN) |
15340 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Coconut oil |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
El-Tantawi, Hala G. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
El-Naggar, Sabry A. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kwilla, Amel M. |
| 9 (RLIN) |
33049 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Khalaf, Amal M. |
| 773 ## - HOST ITEM ENTRY |
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| Title |
Egyptian Journal of Zoology |
| Related parts |
2019.v.71 |
| International Standard Serial Number |
2682-3160 |
| Record control number |
66557 |
| Control subfield |
nnas |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
http://nile.enal.sci.eg/EALE/2019/EJZ/7119/JUN/56.pdf |
| Public note |
Full Text Article |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
alc |
| Articles |
AR |