Normal view MARC view ISBD view

Anti-genotoxic effect of vitamin E administration in acrylamide intoxicated rat bone marrow cells [electronic resource].

By:

El-Tohamy, Amany A

Contributor(s):

Bayomy, Amira A

Language: English Summary language: Arabic Description: p.29-37Other title:

التأثير المضاد للسمية الوراثية للمعاملة بفيتامين "هـ" فى خلايا نخاع عظام الجرذان المسممة بالأكريلاميد [Added title page title]

Uniform titles:

Arab journal of biotechnology, 2008 v. 11 (1) [electronic resource]:

Subject(s):

Online resources:

Full Text Article

In: Arab Journal of Biotechnology 2008.v.11(1)Summary: This study aims to investigate the effect of oral administration of vitamin E (VE, 300 mg/kg, oral intubation daily for 21 consecutive days) to normal and acrylamide-intoxicated (ACR, 25 mg/kg daily for 21 consecutive days) rats. Bone marrow was used to monitor the changes in micronucleus (MN) incidence and modulating the genotoxic effects of gavaged ACR. Treatment of rats with acrylamide (ACR) significantly elevated the frequency of bone marrow MN. Moreover, VE administration decreased the MN frequency to be near the control values; suggesting the ameliorative effect of VE against ACR toxicity.

Average rating: 0.0 (0 votes)

No physical items for this record

Includes references.

This study aims to investigate the effect of oral administration of vitamin E (VE, 300 mg/kg, oral intubation daily for 21 consecutive days) to normal and acrylamide-intoxicated (ACR, 25 mg/kg daily for 21 consecutive days) rats. Bone marrow was used to monitor the changes in micronucleus (MN) incidence and modulating the genotoxic effects of gavaged ACR. Treatment of rats with acrylamide (ACR) significantly elevated the frequency of bone marrow MN. Moreover, VE administration decreased the MN frequency to be near the control values; suggesting the ameliorative effect of VE against ACR toxicity.

Summary in Arabic.

There are no comments on this title.

to post a comment.