Physio-biochemical changes and histological status of the heat stressed rabbit bucks and its amelioration using vitamin E and selenium under Egyptian condition [electronic resouce].

Includes references.

Forty New-Zealand White (NZW) rabbit bucks were used. In the summer season, heat – stressed rabbit bucks were divided into four groups (10 each). The first group was kept as control group. The second, third and fourth groups (treated), were injected intramuscularly with vitamin E (100 IU/head), selenium (0.1 mg/kg body weight) and selenium plus vitamin E weekly at the same dose of the previous groups, respectively. Body thermoregulation, blood haematology and blood components of the summer heat- stressed rabbit bucks (control group) and treated with Vit. E or Se and Vit. E plus Se, were recorded. Histological status of the liver and kidney, were also observed. The results showed that, rectal temperature was significantly (P<0.05) lower, while ear lobe temperature and skin temperature were insignificantly lower of the summer heat-stressed NZW bucks injected with Vit. E or Se alone and Vit. E plus Se than the control group, whereas respiration rate was significantly (P<0.05) lower with the bucks injected by Vit. E plus Se. Haemoglobin concentration (Hb), percentage of packed- cell volume (PCV), red blood cells (RBC’s) and white blood cells (WBC’s) were significantly (P<0.05) higher of the summer heat–stressed NZW bucks injected with Vit. E alone or Vit. E plus Se than those injected with Se alone and the control group. Total protein and albumin concentrations in the blood plasma were significantly (P < 0.05) lower of the summer heatstressed rabbit bucks (control group) and injected with Se alone than those injected with Vit. E alone or Vit. E plus Se. Globulin and urea- N concentrations were significantly (P<0.05) lower of the summer heat– stressed NZW bucks injected with Vit. E alone or Vit. E plus Se than those injected with Se alone and or control group. Cholesterol concentration was significantly (P<0.05) lower of the summer heat–stressed NZW bucks injected with Vit. E or Se alone and Vit. E plus Se than the control group. However, creatinine and total lipids concentrations were significantly (P<0.05) higher of the summer heat-stressed rabbit bucks injected with Vit. E plus Se than those injected with Vit. E or Se alone and the control group. Testosterone concentration was significantly (P<0.05) higher, while cortisol concentration was significantly (P<0.05) lower of the summer heat–stressed NZW bucks injected with Vit. E or Se alone and Vit. E plus Se than the control group. Sodium concentration was significantly (P<0.05) higher, while potassium, calcium and total phosphorus concentrations were significantly (P<0.05) lower of the summer heat-stressed rabbit bucks (control group) than those injected with Vit. E or Se alone and Vit. E plus Se. Aspartate-aminotransferase (AST) and alanine- aminotransferase (ALT) activities were significantly (P<0.05) higher of the summer heat- stressed NZW bucks (control group) and injected with Se alone than those injected with Vit. E alone and Vit. E plus Se. Acid phosphatase (ACP) and alkaline phosphatase (ALP) activities were significantly (P<0.05) higher of the summer heat- stressed NZW bucks (control group) than those injected with Vit. E or Se alone and Vit. E plus Se, however, lactic dehydrogenase (LDH) activity was insignificantly higher. Histological status of the liver and kidney of the summer heat–stressed NZW bucks injected with Vit. E or Se alone and Vit. E plus Se were improved as compared to the control group.

Summary in Arabic.

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