Comparative efficacy of prebiotic mannan-oligosaccharide and diclazuril in chickens experimentally infected with eimeria tenella [electronic resource]

Includes references.

The aim of this study was to use the combination of diclazuril, in a therapeutic dose, plus prebiotic mannan-oligosaccharide (MOS) to control Eimeria tenella infection in Hubbard chickens. One hundred and fifty, one-day old apparently healthy Hubbard chicks were divided into 5 equal groups (30 each). The first group was served as a negative control. The other groups were infected with Ixl05 sporulated oocysts of E. tenella on the 14th day of age. The second group was considered a positive control (infected and non-treated). The third group was fed ration mixed with standard dose of diclazuril (l ppm). The fourth group was fed ration mixed with prebiotic mannan oligosaccharide (MOS) (lg / kg ration). The fifth group was fed ration mixed with diclazuril plus MoS in the same dose and duration. Our results revealed that the combinations of diclazuril plus Mos elicited better anticoccidial effect. These combinations showed a significant increase in body weight, body weight gain, R.B.Cs, W.B.Cs, serum total protein, albumin and globulin. These results were confirmed by the histopathological pictures. It could be inferred that, the anticoccidial effect of diclazuril was enhanced by MOS.

Summary in Arabic.

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