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Immune responses of camels to vaccination with Brucella abortus S19 vaccine [electronic resource].

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Shell, W. S

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Language: English Summary language: Arabic Description: p.158-164Other title:

رد الفعل المناعى للجمال المحصنة بعترة البروسيلا 19 [Added title page title]

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Zagazig veterinary journal, 2009 v. 37 (4) [electronic resource].

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In: Zagazig Veterinary Journal 2009.v.37(4)Summary: Throughout the present work, the humeral and cellular immune responses to Brucella Abortus 19 (S19) vaccine were evaluated in camels. In a group of 10 camels, of about 6 months of age, a dose of 6.2 x 10⁹ CFU was inoculated subcutaneously in each camel while a group of another 5 camels was kept without vaccination as control. Rose Bengal test (RBT) revealed that vaccinated camels began to response to S 19 vaccine by the 2nd week post - vaccination showing detectable antibody levels that began to decrease by the 12th week post- vaccination to reach a zero level by 22 nd week post - vaccination. The results of Indirect ELISA and complement fixation test (CFT) indicated such observation while non vaccinated animals remain sero-negative allover the experimental period. It was noticed that camel cellular immune response to B. Abortus Sl9 vaccine Showed gradual increase through 10 weeks post- vaccination but this response still poor as expected during this period. This study Showed that camel behave as cattle for both humeral and cellular immune response to B. Abortus S19 vaccine.

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Throughout the present work, the humeral and cellular immune responses to Brucella Abortus 19 (S19) vaccine were evaluated in camels. In a group of 10 camels, of about 6 months of age, a dose of 6.2 x 10⁹ CFU was inoculated subcutaneously in each camel while a group of another 5 camels was kept without vaccination as control. Rose Bengal test (RBT) revealed that vaccinated camels began to response to S 19 vaccine by the 2nd week post - vaccination showing detectable antibody levels that began to decrease by the 12th week post- vaccination to reach a zero level by 22 nd week post - vaccination. The results of Indirect ELISA and complement fixation test (CFT) indicated such observation while non vaccinated animals remain sero-negative allover the experimental period. It was noticed that camel cellular immune response to B. Abortus Sl9 vaccine Showed gradual increase through 10 weeks post- vaccination but this response still poor as expected during this period. This study Showed that camel behave as cattle for both humeral and cellular immune response to B. Abortus S19 vaccine.

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