Antibiotic resistance of bacteria implicated in urinary tract infections in diabetic women [electronic resource].

Includes references.

Urinary tract infections are amongst the most common pathogenic infections with an increasing resistence to antimicrobials. Isolates from urine samples were identified and their susceptibility to antimicrobial agents were studied , also synergetic and antagonism of the combined antibiotics against bacterial isolates and electron microscope study against multi-drug resistent bacteria were studied . During the study , 211 urine samples from diabetic and non diabetic female patient were analysed, of which 115 had significant bacteriuria (98 from diabetic and 17 from non diabetic). For diabetic patient, Escherichia coli was the most common etiologic agent 27 (27.6%) followed by Serratia 12(12.2%), Citrobacter, Enterobacter and Micrococci each one was 10(10.2%) , Salmonella 7(7.1%), Pseudomonas aeruginosa and Coagulase negative staphylococci each one was 6(6.1%), Proteus 5(5.1%), Staphylococcus aureus and Shigella each one was 2 (2%) and Streptococci 1(1%), also for non diabetic patient E.coli was the most common etiologic agent 10(58.8%) followed by Enterobacter and Proteus each one was 3 (17.6%) and Streptococci 1(5.9%) . Also we studied the relationship between percentage of infection and age of patients. Amikacin, ciprofloxacin and norfloxacin expressed the most effective antibiotics on these isolates but all these isolates were resistent to ampicillin/ sulbactam, erythromycin, amoxicillin flomocin clavulanic acid and piperacillin except Salmonella was sensitive to amoxicillin flomocin clavulanic acid and Enterobacter was sensitive to piperacillin, the combination between ciprofloxacin and cefotaxim sodium is the most one which showed synergetic against bacterial isolates followed by ciprofloxacin and amikacin and amikacin and nitrofurantion, Pseudomonas aeruginosa was resistent to all antibiotic which used but showed synergetic against the combination between ciprofloxacin and amikacin, ciprofloxacin and norfloxacin, norfloxacin and amikacin and amikacin and nitrofurantion, also, the cell of Pseudomonas aeruginosa appear normal under electron microscope when not treated with norfloxacin but when treated with norfloxacin the cell become longer .

Summary in Arabic.

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