Chromosomal aberrations induced by glyphosate isopropylamine herbicide and trials for diminuting its toxicity using some chemical inactivators and antioxidant [electronic resource] .

Includes references.

Fifty apparently healthy Newzealand white male rabbits (with average weight of 1329 gm) were used in the chronic and acute toxicological studies of Roundup (Glyphosate Isopropylamine) herbicide. Fifteen rabbits were divided into three equal groups, which were used in the chronic cytogenetical (genotoxicological) study, where the group one as a control, the group two administered 750 ppm glyphosate Isopropylamine herbicide in drinking water for 60 days, and the group three administered the herbicide (with the same above dose) along with 312 ppm vitamin-E for 60 days. Results demonstrated the presence of significant structural and numerical chromosomal aberrations in the bone marrow cells of Roundup treated rabbits, and these cytogenetic effects could be partially reduced by vitamin-E treatment.

Summary in Arabic.

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