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Comparative evaluation of the immune efficacy for FMD vaccines prepared with montanide ISA50 and aluminum hydroxide gel in cattle [electronic resource].

By:

Ali, S. M

Contributor(s):

Saad, M. A

Language: English Summary language: Arabic Description: p.221-229Uniform titles:

Veterinary medical journal, 2005 v.53 (2) Part 1 [electronic resource]:

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In: Veterinary Medical Journal 2005.v.53(2)Summary: Montanide ISA50 and Aluminum hydroxide gel were used as adjuvant for preparation of FMD vaccine. The vaccines wcre tested in Guinea pigs and cattle.Serum neutralization test and indirect ELISA were carried out to follow up the immune status of vaccinated cattle for 30 weeks post vaccination (WPV).The revealed rcsults indicatc that the vaccine emulsified with Montanide ISA50 adjuvant appeared to be more potent and gave a higher level of immunity to the vaccinated cattle than that produced from AL (OH) 3 gel vaccinc till the end of the 30 (WPV). Also that indicates the ability of Montanide ISA50 oil adjuvant vaccine for serological responses toFMD antigens more than AL (OH) 3 gel adjuvant vaccine.

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Montanide ISA50 and Aluminum hydroxide gel were used as adjuvant for preparation of FMD vaccine. The vaccines wcre tested in Guinea pigs and cattle.Serum neutralization test and indirect ELISA were carried out to follow up the immune status of vaccinated cattle for 30 weeks post vaccination (WPV).The revealed rcsults indicatc that the vaccine emulsified with Montanide ISA50 adjuvant appeared to be more potent and gave a higher level of immunity to the vaccinated cattle than that produced from AL (OH) 3 gel vaccinc till the end of the 30 (WPV). Also that indicates the ability of Montanide ISA50 oil adjuvant vaccine for serological responses toFMD antigens more than AL (OH) 3 gel adjuvant vaccine.

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