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Sperm DNA damage and embryonic development as related to fertility potential of buffalo bulls [electronic resource].

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Eid, Laila N

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Language: English Summary language: Arabic Description: P. 65-74Other title:

تكسر المادة الوراثية فى الحيوان المنوى وعلاقتها بخصوبة الطلوقة ومقدرة الاجنة على التطور [Added title page title]

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Mansoura University journal of animal and poultry production, 2011 v.2 (5) [electronic resource].

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In: Mansoura University Journal of Animal and Poultry Production 2011.v.2(5)Summary: Conventional semen analysis are not sufficient to evaluate bull's fertility, however it might be used as a preliminary evaluation for predicting fertility potential. Sperm DNA integrity may give a better evaluation of bull fertility potential. In the current study, six mature buffalo bulls were divided into two groups (based on a threshold of 70% motility; as high or low potential fertility). The first objective of the current study was to evaluate DNA fragmentation (measured as Comet value) in the two groups of bulls (three bulls/group) in relation to its potential fertility. The results showed that low potential fertility bulls had significantly (P<0.05) more sperm DNA damage; higher (P<0.05) sperm abnormal morphology and lower (P<0.05) sperm viability than that of sperm from the high potential fertility bulls. Our second objective was to assess whether a relationship exists between bull's sperm DNA damage and bull in vitro fertility.

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Conventional semen analysis are not sufficient to evaluate bull's fertility, however it might be used as a preliminary evaluation for predicting fertility potential. Sperm DNA integrity may give a better evaluation of bull fertility potential. In the current study, six mature buffalo bulls were divided into two groups (based on a threshold of 70% motility; as high or low potential fertility). The first objective of the current study was to evaluate DNA fragmentation (measured as Comet value) in the two groups of bulls (three bulls/group) in relation to its potential fertility. The results showed that low potential fertility bulls had significantly (P<0.05) more sperm DNA damage; higher (P<0.05) sperm abnormal morphology and lower (P<0.05) sperm viability than that of sperm from the high potential fertility bulls. Our second objective was to assess whether a relationship exists between bull's sperm DNA damage and bull in vitro fertility.

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