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Haematological, biochemical and histopathological alterations induced by abamectin and Bacillus thuringiensis in male albino ratsl [electronic resource].

By:

Eissa, F.I

Contributor(s):

Zidan, N.A

Language: English Summary language: Arabic Description: p.507-521Other title:

التغيرات الهيماتولوجية والبيوكيميائية والهستوباثولوجية فى ذكور الفئران البيضاء الناجمة عن الابامكتين والباسيلس ثيورينجينسيس [Added title page title]

Uniform titles:

Journal of agricultural research Tanta University, 2006 v.32 (2) [electronic resource].

Subject(s):

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In: Journal of Agricultural Research Tanta Univeristy 2006.v.32(2)Summary: and hepato-toxicity induced by abamectin pesticide (Vertimec) and a commercial formulation of a bio¬insecticide Bacillus thuringiensis (Agerin) in male albino were evaluated. Blood picture and blood glucose level were investigated as well. Male albino rats were administered daily dietary doses each equivalent to 1110 or 11100 of the LDso values of each toxicant. Treatments continued for 30 consecutive days. Abamectin was found to pose risks of renal and hepato-toxicity in rats. Since biochemical parameters of liver function (i.e. aspartate aminotransferase activity, alanine aminotransferase activity, acid phosphatase activity, albumin, and total protein levels) and kidney function (uric acid and creatinine concentration) were severely affected. These effects were ensured by histopathological examination of liver and kidney tissues. Likewise, some haematological indices (i.e, erythrocyte count, leukocyte count and haemoglobin concentration) were also influenced, in addition abamectin might be hypoglycemic. On the other hand, the above mentioned lesions were relatively obscure in the case of Bacillus thuringiensis-treated rats.

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and hepato-toxicity induced by abamectin pesticide (Vertimec) and a commercial formulation of a bio¬insecticide Bacillus thuringiensis (Agerin) in male albino were evaluated. Blood picture and blood glucose level were investigated as well. Male albino rats were administered daily dietary doses each equivalent to 1110 or 11100 of the LDso values of each toxicant. Treatments continued for 30 consecutive days. Abamectin was found to pose risks of renal and hepato-toxicity in rats. Since biochemical parameters of liver function (i.e. aspartate aminotransferase activity, alanine aminotransferase activity, acid phosphatase activity, albumin, and total protein levels) and kidney function (uric acid and creatinine concentration) were severely affected. These effects were ensured by histopathological examination of liver and kidney tissues. Likewise, some haematological indices (i.e, erythrocyte count, leukocyte count and haemoglobin concentration) were also influenced, in addition abamectin might be hypoglycemic. On the other hand, the above mentioned lesions were relatively obscure in the case of Bacillus thuringiensis-treated rats.

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