Effects of biogen® and levamisol hcl® on the immune response of cultured Oreochromis niloticus to Aeromonas hydrophila vaccine [electronic resource].

Includes references.

The effect of Biogen (2 g/kg feed) and levamisol HCI (1g/kg feed) on phagocytic assay, activities of serum enzymes (S.GOT, S.GPT, ALP), cholesterol, creatinine, glucose, total proteins, albumin, globulin and antibody titers before and after immunization of Oreochromis niloticus (O. niloticus) by intramuscular injection (IM) with formalin killed Aeromonas hydrophila vaccine were studied. The results proved that Biogen and levamisol HCL causes a marked immunopotentiating effect more than control after IM vaccination. The immunopotentiating effect ofBiogen and levamisol HCL covered both, the humoral and cell- mediated immune response and a marked rise in the antibody titers at day 70 after vaccination which reached to 9.0 ± 0.0 and 9.0 ± 0.0 after IM vaccination respectively, compared to the vaccinated control group (6.5 ± 0.5). Also. phagooytic activity obtained from fish, fed with ration supplemented with Biogen and levamisol HCL was significantly increased than ration supplemented with basal diet (control group). The results of enzyme activities (ALP, S.GOT, S.GPT) and creatinine, cholesterol, glucose as well as total proteins, albumin and globulin prove that the group fed with ration containing Biogen and Levamisol HCL were similar to control group in enzyme activities.

Summary in Arabic.

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