Biological studies on some soft drinks [electronic resource].

Includes references.

The aim of the study was to determine bone mineral density changes caused by consumption of cola, orange and soda soft drinks and the associated factors. Twenty Sprague-Dawley rats were divided into four groups. Groups 1 fed on basal diet as control and the other groups were fed basal diet and received 4ml soft drink /day / rat for 6 weeks. The bone mineral density of the rats was measured using Dual Energy X-ray Absorptiometry at the end of 6 weeks. The blood values and weights of the animals were also determined. The kidneys were removed for histopathological examination. The weight gain was higher in the groups consuming cola drinks than the control group and the other group rats (P s 0.05). No significant change was detected in the blood calcium levels. There was a significant decrease in the bone mineral density of test groups when compared to the control groups (P s 0.05). While the examination of the kidneys revealed general glomerular congestion and intertubular bleeding. So, it could be concluded that the decrease in bone mineral density might be related to the renal damage caused by soft drinks especially cola in addition to other related factors.

Summary in Arabic.

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