Effect of dopamine antagonist (Domperidone) treatment on induction of ovulation in anestrous mares [electronic resource].
Language: English Summary language: Arabic Description: p. 13-20Other title:- تأثير استخدام العلاج بمضادات الدوبامين(دومبيريدون)على حث التبويض فى حالة اتعدام الشبق في الأفراس [Added title page title]
- Veterinary medical journal, 2017 v.63 (3) [electronic resource].
| Item type | Current library | Call number | Status | Date due | Barcode | |
|---|---|---|---|---|---|---|
Articles
|
Main | ART VMJ V63 NO3 3 (Browse shelf(Opens below)) | Available |
Includes references.
The current study is an endeavor for profound understanding some hormonal and biochemical constituents during induction of
ovulation in anestrous mares by using domperidone (Dopamine antagonist). Fifteen anestrous pure Arabian mares divided randomly
into 2 groups, group (1) five mares and serve as a control, while Group (2) ten mares treated with 1.1 mg/kg domperidone for 25 days.
Ultrasonographic scan was performed twice per week for detection of ovarian activity and follicular growth. Blood samples were collected
one month before the treatment for 3 times with 10 days intervals for detection of progesterone, and twice per week after treatment till
10 days after the end of treatment for determination of progesterone, estrogen and prolactin hormones in addition to total protein, total
cholesterol and triglycerides, before and after response for treatment. Eight mares (80%) showed ovulation and CL formation from the domperedone
treated group while 2 mares (20%) showed no large follicles formation till the end of the trial period. The obtained results showed a significant
increase in progesterone, estradiol and prolactin concentration in treated group compared to control one at 3rd and 4th week from treatment,
while cholesterol level showed significant increase in treated group compared to control at 3rd week of treatment. And non significance change
was recorded in protein and triglycerides levels. We can conclude that using Dopamine antagonist (Domperidone) is effective alternative for
induction of ovulation in anestrous Arabian mares under Egyptian circumstances.
Summary in Arabic.
There are no comments on this title.