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Somatic mutations identification of FGFR3 among HCC egyptian patients using NGS [electronic resource]

By:

Elfeky, Ahmed M

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Language: English Summary language: Arabic Description: 103 - 111 pUniform titles:

Egyptian journal of genetics and cytology, 2022. v. 51 (2)

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Full Text Article

In: Egyptian Journal of Genetics and Cytology 2022.v.51(2)Summary: Hepatocellular carcinoma (HCC) is the most prominent liver cancer, accounting for 85% of primary liver malig-nancies. It is a very aggressive tumor, hav-ing a terrible prognosis and poor survival rate (Mir et al., 2021). HCC is ranked the sixth most common type of cancer and the third leading cause of cancer-related mortali-ties worldwide (Singh et al., 2020). HCC incidences arise in complica-tions associated with chronic liver disease like cirrhosis, endemic hepatitis B virus (HBV)/hepatitis C virus (HCV) infections, nonalcoholic fatty liver disease, and alcohol-related liver disease (Torre et al., 2015). Keywords: Hepatocellular carcinoma, Next generation sequencing, fibroblast growth factor receptor 3.

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Hepatocellular carcinoma (HCC) is the most prominent liver cancer, accounting for 85% of primary liver malig-nancies.
It is a very aggressive tumor, hav-ing a terrible prognosis and poor survival rate (Mir et al., 2021). HCC is ranked the sixth most common type of cancer and the third leading cause of cancer-related mortali-ties worldwide (Singh et al., 2020).
HCC incidences arise in complica-tions associated with chronic liver disease like cirrhosis, endemic hepatitis B virus (HBV)/hepatitis C virus (HCV) infections, nonalcoholic fatty liver disease, and alcohol-related liver disease (Torre et al., 2015).
Keywords: Hepatocellular carcinoma, Next generation sequencing, fibroblast growth factor receptor 3.

Summary in Arabic

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