Micro rna192 evaluation as early diabetic ret-inopathy diagnostic biomarker in egyptian patients with type 2 diabetes mellitus [electronic resource]
Language: English Summary language: Arabic Description: 21 - 32 pUniform titles:- Egyptian journal of genetics and cytology, 2022. v. 51 (1)
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Main | ART EJGC V51 No1 2 (Browse shelf(Opens below)) | Available |
Includes bibliographic reference
Diabetes is a major and quickly spreading health issue on a global scale. One of the most prevalent metabol-ic illnesses in the world is Type 2 Diabe-tes Mellitus (T2DM), which is primarily brought on by the interaction of two key factors: impaired insulin production by pancreatic beta-cells and impaired insulin sensitivity in tissues (Roden and Shulman, 2019).
About 90-95% of all instances of diabetes worldwide are T2DM, and this number is continually rising (Hegazi et al., 2015).
With approximately 8,850,400 cases and an adult prevalence of 15.2%, Egypt ranks ninth globally (Azzam et al., 2021).
Microvascular problems including retinopathy, nephropathy, and neuropathy as well as macrovascular consequences are all highly correlated with T2DM (An et al., 2021).
Keywords: Diabetes Mellitus, miRNA 192, Diabetic Retinopathy, Gene regulation.
Summary in Arabic
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