Dietary administration of undenatured whey protein decreased the histopathological changes induced by ciprofloxacin in hepatic, renal and ilael tissues of mice [electronic resource].

Includes references.

Whey protein contains all amino acids that are necessary for nonnal cell growth. This work aimed to study whether whey protein can decrease the effects induced by Ciprofloxacin. Histological, histochemical and immunological methods were used. Mice were classified into a control (group I) and three treated groups. Group II was daily administrated Ciprofloxacin for 7 days. Group III was administrated Ciprofloxacin and synergistically mice administrated whey protein for the 7 days. Mice of group IV were treated in the same way like as those of group III with the whey protein continue for 8 days more (whey protein was administrated 15 days in group IV instead -of 7 days in group III). Liver sections of group II revealed that cell boundaries of hepatocytes became unclear, blood sinusoids became narrow and Kupffer cells increased in both size and number. PAS stain showed a reduced carbohydrate content in group II, while it showed a little improved in group IV.

Summary in Arabic.