Evaluation of parenteral treatment of colibacillosis in pre-weaning buffalo calves using amoxicillin and clavulinic acid (synulox®) [electronic resource].

Includes references.

Thirty, 1-2 month old pre-weaning Egyptian buffalo calves in a private farm at Sharkia Governorate were divided into naturally diarrheic calves and non diarrheic calves were subdivided into two equal groups. The [lISt group was treated intramuscular (11M) with amoxicillin suspension (c1amoxyl L.A ®) at a dose level of hnl / 15Kg B.wt . and the second group was treated 11M with amoxicillin potentiated c1avulinic acid (Synulox ®) at dose of Iml / 20 kg for 3 successive days. Rectal swabs were aseptically collected from diarrheic and healthy calves. Bacteriological examination of isolates revealed that E.coli strains were the main causative agent of diarrhea in diseased calves. Susceptibility of isolated strains to different antimicrobials was conducted and showed that amoxicillin potentiated with c1avulinic acid was highly effective. Blood samples from studied calves before and after treatment were collected for biochemical and hematological studies. In diseased calves, a significant decrease in serum total protein with its albumin and globulin in addition to immunoglobulin, hemoglobin decreases also were recorded. While leukocytosis and significant increases in platelets were noticed. A non significant decrease in sodium with a significant decrease in potassium were recorded in diseased calves. Parenteral treatment of diarrheic calves with arnoxicillin potentiated with c1avulinic acid was more effective than amoxicillin alone in reducing the clinical symptoms and improvement of general health conditions.

Summary in Arabic.

1