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The antioxidant and anticancer activities of strawberry seedling (Fragaria X ananassa c .v. Sweet Charlie) extracts [electronic resource].

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Hemmat, A

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Language: English Summary language: Arabic Description: p.355-380Other title:

أنشطة مستخلصات بادرات الفراولة (صنف سويت شارل) كمضادات للأكسدة و مضادات للسرطان [Added title page title]

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Journal of biological chemistry and environmental sciences, 2008 v. 3 (2) Part III [electronic resource].

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In: Journal of Biological Chemistry and Environmental Sciences 2008.v.3(2)IIISummary: Studies were conducted to evaluate the antioxidant and anticancer activities of strawberry seedlings shoots extracts (SS) and strawberry seedlings roots extracts (SR) using different solvent systems. SS and SR extracts had high antioxidant activity % on linoleic acid system, where butanol fraction (BUF) of SR had the most antioxidant activity (IC 50=28.32 μg /ml) In comparison with BHT (IC 50=31.5 μg/ml) and BHA (IC 50=33.75 μg /ml). SS AND SR extract had high scavenging activity on di phenyl picryl hydrazyl (DPPH) radical, where the highest scavenging activity was observed in butanol fraction (BUF) of SS (93.55%) followed by ethyl acetate fraction (EAF) of SS (93.16%), EAF of SR (93.08%) and BUF of SR (92.79%) at concentration 25 μg /ml while ascorbic and BHT had lower scavenging activity (90.30% and 90.80% respectively) The observed data revealed a positive relationship between antioxidant activity and the extracts content of total phenols and flavonoids and also between reducing power value. The obtained result showed that SS fractions had a higher anti cancer activity than SR fractions where EAF of SS had the highest anticancer activity (81.70%) while EAF of SR had (53.18 %) at concentration 10 μg/ml. No relationship between anticancer activity and antioxidant activity of extract. Key words: Antioxidant Activity, Scavenging Activity Lipid Peroxidation, Anticancer Activity, Strawberry.

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Studies were conducted to evaluate the antioxidant and anticancer activities of strawberry seedlings shoots extracts (SS) and strawberry seedlings roots extracts (SR) using different solvent systems. SS and SR extracts had high antioxidant activity % on linoleic acid system, where butanol fraction (BUF) of SR had the most antioxidant activity (IC 50=28.32 μg /ml) In comparison with BHT (IC 50=31.5 μg/ml) and BHA (IC 50=33.75 μg /ml). SS AND SR extract had high scavenging activity on di phenyl picryl hydrazyl (DPPH) radical, where the highest scavenging activity was observed in butanol fraction (BUF) of SS (93.55%) followed by ethyl acetate fraction (EAF) of SS (93.16%), EAF of SR (93.08%) and BUF of SR (92.79%) at concentration 25 μg /ml while ascorbic and BHT had lower scavenging activity (90.30% and 90.80% respectively) The observed data revealed a positive relationship between antioxidant activity and the extracts content of total phenols and flavonoids and also between reducing power value. The obtained result showed that SS fractions had a higher anti cancer activity than SR fractions where EAF of SS had the highest anticancer activity (81.70%) while EAF of SR had (53.18 %) at concentration 10 μg/ml. No relationship between anticancer activity and antioxidant activity of extract. Key words: Antioxidant Activity, Scavenging Activity Lipid Peroxidation, Anticancer Activity, Strawberry.

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