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Mitotic gene conversion and monosomics induced in yeast by cypermethrin and calmepam [electronic resource].

By:

Al-Ayoubi, Dujana Yahya

Language: English Summary language: Arabic Description: p.433-450Other title:

التحول الجينى الميتوزى وأحاديات الكروموسوم المستحدثة فى الخميرة بالسيبرميترين والكالميبام [Added title page title]

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Journal of the advances in agricultural researches, 2003 v. 8 (3) [electronic resource].

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In: Journal of the advances in agricultural researches 2003.v.8(3)Summary: The present investigation was planned to study the possible genotoxic effect Induced by the Insecticide cypermethrin and the drug calmepam upon yeast genome. In order to achieve such a purpose three yeast strains were employed. These strains are: 1-JD1 strain: 2-D7; and 3-D61-m strain. JD1 as well as D7 were used to investigate the convertogenic effect. D7 cells were used to study the effect of the tested chemicals upon mitotic crossing over. D61-m strain was used to study the clastogenlc activity of the chemicals by measuring chromosome loss or Induction of monosomics. The results obtained showed that the ten tested concentrations of both chemicals are toxic, since significant decreases in survivors were observed.

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The present investigation was planned to study the possible genotoxic effect Induced by the Insecticide cypermethrin and the drug calmepam upon yeast genome. In order to achieve such a purpose three yeast strains were employed. These strains are: 1-JD1 strain: 2-D7; and 3-D61-m strain. JD1 as well as D7 were used to investigate the convertogenic effect. D7 cells were used to study the effect of the tested chemicals upon mitotic crossing over. D61-m strain was used to study the clastogenlc activity of the chemicals by measuring chromosome loss or Induction of monosomics. The results obtained showed that the ten tested concentrations of both chemicals are toxic, since significant decreases in survivors were observed.

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