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Cytokines levels in mice intoxicated with diazinon [electronic reource].

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Alluwaimi, A. M

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Language: English Description: p.201-206Uniform titles:

Alexandria journal of veterinary science, 2001 v. 17 (1) [electronic reource].

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In: Alexandria Journal of Veterinary Science 2001.v.17(1)Summary: The effect of diazinon on the levels of different cytokines in mice was studied. Two groups of mice were administered with diazinon in the dose of 1/5 LD₅₀ for 5 and 15 days respectively. IL-2, IL- 4, IL-10 and IFN-γ levels were determined. The levels of cytokines in the intoxicated mice were determined day 5 and day 15 post- inoculation.IL-2 and IL-4 were not detected in all samples of intoxicated mice. However, IL-10 and IFN-γ were significantly decreased in both groups of mice intoxicated with diazinon. The significant reduction of IL-10 and IFN-γ was discussed.

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The effect of diazinon on the levels of different cytokines in mice was studied. Two groups of mice were administered with diazinon in the dose of 1/5 LD₅₀ for 5 and 15 days respectively. IL-2, IL- 4, IL-10 and IFN-γ levels were determined. The levels of cytokines in the intoxicated mice were determined day 5 and day 15 post- inoculation.IL-2 and IL-4 were not detected in all samples of intoxicated mice. However, IL-10 and IFN-γ were significantly decreased in both groups of mice intoxicated with diazinon. The significant reduction of IL-10 and IFN-γ was discussed.

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