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Preliminary preparation and evaluation of a local lysate vaccine for protection of chicken against E. cli infection [electronic resource].

By:

Helmy ,Noha A

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Language: English Summary language: Arabic Description: P.365-375Other title:

تحضير وتقييم للقاح محلى من محلالات الخلايا البكتيرية لوقاية الدواجن ضد الاصابة ببكتريا القولون المعوى [Added title page title]

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Veterinary medical journal, 2007 v.55 (2) [electronic resource].

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In: Veterinary Medical Journal 2007.v.55(2)Summary: Four serotypes of E. coli (01,02,06 and 0128) were used in preparation of a local polylysate oil vaccine that was evaluated in comparison with a licensed imported one for protection of chicken against E. coli infection. Five groups, each of 20 chickens were vaccinated with the local vaccine subcutaneously (SIC) and intramuscularly (11M) using single or double vaccinal dose and boostered after 2 weeks. Vaccinated and control chickens were challenged 2 weeks post second vaccination with the four virulent E. coli strains. No deaths occurred in all vaccinated chickens except one death case in one group. Survivors were necropsied one week post challenge. No gross lesions were observed in all vaccinated groups compared to those of non-vaccinated one.

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Four serotypes of E. coli (01,02,06 and 0128) were used in preparation of a local polylysate oil vaccine that was evaluated in comparison with a licensed imported one for protection of chicken against E. coli infection. Five groups, each of 20 chickens were vaccinated with the local vaccine subcutaneously (SIC) and intramuscularly (11M) using single or double vaccinal dose and boostered after 2 weeks. Vaccinated and control chickens were challenged 2 weeks post second vaccination with the four virulent E. coli strains. No deaths occurred in all vaccinated chickens except one death case in one group. Survivors were necropsied one week post challenge. No gross lesions were observed in all vaccinated groups compared to those of non-vaccinated one.

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