Evaluate the health impact of some vegetable wastes on liver disorder of rats pretreated with CCL4 [electronic resource].

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This study was conducted to investigate to possible health action of some plant leaves for impaired liver function of injected rats with carbon tetrachloride (CCL4). Thirty five mature albino rats weighting (150±10) g.B.Wt. each, were used and divided to 7 equal group, one was kept as control- ve group. The other 6 groups were injected s/c by carbon tetrachloride (CCL4) in olive oil 50% (3ml/ kg. B. Wt.). Administration of single dose per day of CCl4 to a rats, twice a week for 3 weeks to induce hepatotoxicity in laboratory animals was carried out. The used plants leaves were given at 7.5% from (Mango Tree leaves, Pear Tree leaves, Leek Leaves and Pomegranate Peels, and also as a mixture of all). At the end of experimental period (28 day), animal were scarified; Blood samples were collected to determine the following parameters: Antioxidant Enzymes (SOD, CAT, GST), level of serum liver enzymes (ALT,AST,ALP) and AST/ALT, serum total protein, serum albumin, serum globulin ,total bilirubin , total cholesterol,triglycerides, lipoprotein fractions (HDL-c, LDL-c and VLDL-c), atherogenic index(AI), uric acid ,urea nitrogen, creatinine .Mango tree leaves and Pomegranate peels showed gradual decreases in total cholesterol level and Pear tree leaves recorded the best results in the improvement of liver enzymes while leek leaves showed improvement of liver and kidney function.

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