Comparative efficacy of different toltrazuril doses against coccidiosis in broiler chickens [electronic resource].

Includes references.

The present study was designed to evaluate the therapeutic and prophylactic efficacy of Toltrazuril at different doses against coccidiosis. One hundred and twenty, one day old chicks, were divided into 6 groups, each of 20 chicks. Group A was left as noninfected non-medicated control. Chicks of group B were infected and non-medicated while chicks of group C, D, and E were treated with Toltrazuril in drinking water at rate of 7 (25ppm), 3.5 (12.5ppm), and 1.75 (6.25ppm) mg/kg body weight on day 18 and 19, 25 and 26 respectively. In chicks of group F, Toltrazuril was given as prophylactic at rate of 7mg/kg body weight on days 3 and 10. Chicks of groups (B, C, D, E and F) were challenged orally with 20,000 sporulated oocysts of E. tenella on the 16th and 26th day of their age. Evaluation of the Toltrazuril efficacy was based on oocysts counts per gram (OPG) of faeces, weight gain, mortality and postmortem findings. The maximum reduction of OPG counts were detected in group D (98.04%) and group E (85.39%). Concerning the mean body weight gains as compared to healthy control, group D showed best performance, followed by group E, group C and group F. Chicks of group B showed lowest performance. Conclusions: Ultimately, it was concluded that Toltrazuril at rate of 3.5 mg/kg would be the best solution to solve coccidiosis problem.

Summary in Arabic.

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