Potential role of jasonia montanta and jasonia candicans against alzheimer's disease: Assessment of oxidative stress and gene expression changes in ad-induced rats [electronic resource].

Includes references.

Oxidative stress-induced damage was shown to be one of the important mechanisms to indicate that aluminum has an association with the etiology of Alzheimer's disease (Kumar et al., 2009). Increased generation of reactive oxygen species (ROS) and lipid peroxidation has been found to be involved in the pathogenesis of many diseases of known and unknown etiology and in the toxic actions of many compounds (Andallu and Varadacharyulu, 2003). Aluminium is a nonredox active metal which is capable of increasing the cellular oxidative milieu by potentiating the pro-oxidant properties of transition metals such as iron and copper (Bjertness et al., 1996).

1