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Induction of Cephalosporin C in Cephalosporium acremonium using u.v. light and selection of a mutant that showed highest fermentation capability [electronic resource].

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Hassanein, S. H

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Language: English Summary language: Arabic Description: P.35-55Other title:

حث انتاج السيفالوسبورين من فطر السيفالوسبوريوم أكريمونيوم بواسطة الأشعة فوق البنفسجية وانتخاب طفرة ذات أعلى قدرة تخمر.‪ [Added title page title]

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Minufiya journal of agricultural research, 2009 V. 34 (1) Part one [electronic resource].

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In: Minufiya journal of agricultural research 2009.v.34(1)P.1Summary: Ultraviolet-Ligh mutagenesis had been used in the induction of cephalosporin c (CPC) production in cephalosporium acremonium atcc 11550. selection of high antibiotic-producers among the mutants was carried out by agar diffusion method using bacillus subtilis atcc 6633, and then final selection of the highest cpc producing mutant was carried out in shake flasks in which it produced 900 mg/L. the newly-isolated mutant (M104) produced 2160 mg/L CPC in a batch process in NBS stirred-tank bioreactor(working volume 4L).

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Ultraviolet-Ligh mutagenesis had been used in the induction of cephalosporin c (CPC) production in cephalosporium acremonium atcc 11550. selection of high antibiotic-producers among the mutants was carried out by agar diffusion method using bacillus subtilis atcc 6633, and then final selection of the highest cpc producing mutant was carried out in shake flasks in which it produced 900 mg/L. the newly-isolated mutant (M104) produced 2160 mg/L CPC in a batch process in NBS stirred-tank bioreactor(working volume 4L).

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