Experimental studies on the effect of neomycin B on rotavirus replication (Record no. 45310)

MARC details
000 -LEADER
fixed length control field 02398cab a2200337Ia 45 0
001 - CONTROL NUMBER
control field u190772
003 - CONTROL NUMBER IDENTIFIER
control field SIRSI
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110329s2009 ua ss b eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EAL
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
Language code of summary or abstract ara
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) ART ZVJ V37 No4 14
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Salama, Ali A.
240 10 - UNIFORM TITLE
Uniform title Zagazig veterinary journal, 2009 v. 37 (4)
Medium [electronic resource].
245 10 - TITLE STATEMENT
Title Experimental studies on the effect of neomycin B on rotavirus replication
Medium [electronic resource].
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسات تجريبية على تأثير النيوميسين-بى على تكاثر فيروس الروتا.
300 ## - PHYSICAL DESCRIPTION
Extent p.137-144.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Includes references.
520 ## - SUMMARY, ETC.
Summary, etc. Bovine Rotavirus (BRV) is a major cause of acute gastroenteritis in newborn calves throughout the world causing economic losses to beef and dairy industries. Neomycin B, an aminoglycoside antibiotic has been shown to inhibit rotavirus replication in-vitro. The current study was carried out to study the availability of neomycin B as preventive and chemotherapeutic mean for rotavirus infection, It was conducted by following up the replication of virus inside the infected and infected treated mice. Moreover the shedding of virus by infected and infected treated mice was determined by immunofluorescence (IF). The group of mice inoculated with BRV and simultaneously treated with neomycin had significant reductions in virus shedding by 1.43 and 1.7 logs at first day and 5th day post BRV inoculation respectively. It was revealed that neomycin has an interfering effect on rotavirus replication in-vivo (in mice), when the drug administered before, during and after viral infection. Further studies for field applications of neomycin as therapeutic measure for Bovine Rotavirus infection in newborn calves especially in calves born from non vaccinated animals or born with low titer of antibodies need to be done.
546 ## - LANGUAGE NOTE
Language note Summary in Arabic.
596 ## -
-- 1
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rotaviruses.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Viruses
General subdivision Reproduction.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neomycin.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aminoglycosides
General subdivision Therapeutic use.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Calves
General subdivision Vaccination.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ali, Ahmed Abdel Samie H.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zeidan, Sayed M.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mansour, Shimaa M.G.
773 0# - HOST ITEM ENTRY
Title Zagazig Veterinary Journal.
Related parts 2009.v.37(4)
International Standard Serial Number 1110-1458
Control subfield nnas
Record control number u189860
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://nile.enal.sci.eg/EALE/2009/ZVJ/3709/4/137.pdf">http://nile.enal.sci.eg/EALE/2009/ZVJ/3709/4/137.pdf</a>
Public note Full Text Article
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Articles
Source of classification or shelving scheme Library of Congress Classification

No items available.


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