Studies on alternative methods for titration of virulent FMD virus type "0" [electronic resource].

By: Contributor(s): Language: English Summary language: Arabic Description: p.123-129Other title:
  • دراسة عن الطرق البديلة لمعايرة الفيروس الضارى لمرض الحمى القلاعية للعترة "0" [Added title page title]
Uniform titles:
  • Zagazig veterinary journal, 2010 v. 38 (2) [electronic resource].
Subject(s): Online resources: In: Zagazig Veterinary Journal 2010.v.38(2)Summary: The historical background of FMD vaccine production is briefly described, improvement Achieved through the use of monolayer and suspension cultures outlined elements that are crucial in the production of modem vaccines are discuss such as inactivation of viral antigen, successive concentration and purification of the antigen and the final formulation of the vaccine. To evaluate such vaccine we must be have an identified virulent FMD virus with accurate titer which is the backbone in potency test for evaluation of FMD vaccine these studies shows the comparative between titration of virulent FMDV type 01/3/93 Egypt in cattle and mice.
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The historical background of FMD vaccine production is briefly described, improvement Achieved through the use of monolayer and suspension cultures outlined elements that are crucial in the production of modem vaccines are discuss such as inactivation of viral antigen, successive concentration and purification of the antigen and the final formulation of the vaccine. To evaluate such vaccine we must be have an identified virulent FMD virus with accurate titer which is the backbone in potency test for evaluation of FMD vaccine these studies shows the comparative between titration of virulent FMDV type 01/3/93 Egypt in cattle and mice.

Summary in Arabic.

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