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Effect of streptomycin sulphate and chloramphenicol sodium succinate on immune response [electronic resource].

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Sedik, M. Z

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Language: English Summary language: Arabic Description: p.327-332Other title:

تأثير سلفان الاستريبتوميسين والكلورامفينيكول صوديوم على الاستجابة المناعية [Added title page title]

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Bulletin of Faculty of Agriculture. Cairo University, 2012 v. 63 (3) [electronic resource].

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In: The Bulletin Faculty of Agriculture, Cairo University 2012.v.63(3)Summary: Streptomycin and chloramphenicol are antibiotic drugs.Streptomycin is the first of a class of drugs called aminoglycosides to be discovered, as well as was the first antibiotic used for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Moreover, chloramphenicol was originally produced by Streptomyces venezuelae. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracycline's. Because both antibiotics are cheap and easy to manufacture, they are frequently found as a drug of choice in the third world. Streptomycin Sulphate (100mg/kg) and chloramphenicol SodiumSuccinate (200mg/kg) , were used to study their effect on immune response by measuring different immune parameters like total WBC's and total globulin. Bacterial antigens applied in this study were two bacterial strains (Bacillus spp. and Pseudomonas spp.).The results obtained indicated that, there was a change in various data record, which means there was a suppression in the immune response of the body.

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Streptomycin and chloramphenicol are antibiotic drugs.Streptomycin is the first of a class of drugs called aminoglycosides to be discovered, as well as was the first antibiotic used for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Moreover, chloramphenicol was originally produced by Streptomyces venezuelae. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracycline's. Because both antibiotics are cheap and easy to manufacture, they are frequently found as a drug of choice in the third world. Streptomycin Sulphate (100mg/kg) and chloramphenicol SodiumSuccinate (200mg/kg) , were used to study their effect on immune response by measuring different immune parameters like total WBC's and total globulin. Bacterial antigens applied in this study were two bacterial strains (Bacillus spp. and Pseudomonas spp.).The results obtained indicated that, there was a change in various data record, which means there was a suppression in the immune response of the body.

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