Comparative efficacy evaluation of Moxidectin and ivermectin injectable formulation against helminthes infestation of donkeys (Equus asinus) in Sudan [electronic resource].

Includes references.

A total of24 male and female donkeys of local breed, 4-10 years ofage and naturally infected with helminth parasites was utilized in a controlled study to evaluate the efficacy of Moxidectin injectable formulation at the dosage of 0.2 mg/kg of live weight used either subcutaneously or intramuscularly and an ivermectin injectable formulation at the dosage of 0.2 mg per Kg applied subcutaneously. Animals were allocated randomly into four groups of six donkeys each, and treatments were randomized among the groups. One group was kept as untreated control. The experiment extended for 14 days. Faecal samples were collected at day 0 (before treatment), and then at 1,2,3,7 and 14 days post treatment. The number ofparasites remaining in each animal was determined after necropsy of the animals at day 14 post treatment for all donkeys. Both Moxidectin subcutaneously or intramuscularly and ivermectin administered subcutaneously reduced initial EPG from a mean of 550,700, and 600 to 50 (90.9%), 150 (78.5%), and zero (100%) at the end of trial on day 14.

Summary in Arabic.