Pathological and clinco-pathological studies on the effect of introducing pituitary gland DNA as foreign genes in a local chicken breed [electronic reource].

By: Contributor(s): Language: English Description: p.171-181Uniform titles:
  • Alexandria journal of veterinary science, 2001 v. 17 (1) [electronic reource].
Subject(s): Online resources: In: Alexandria Journal of Veterinary Science 2001.v.17(1)Summary: The experiment was conducted as an attempt to introduce DNA of pituitary glands either from broiler chicks (males or females) or turkey at market age into eggs of Montazah chickens (embryo cells) at the third day of incubation. Several hematological and biochemical parameters as well as histopathological changes in different organs were studied on the hatched chicks at different ages. The results showed that the introduction of foreign DNA had different expression of protein and lipid synthesis. The DNA injected chicks had the highest globulin concentrations (P<0.05), while it had insignificant differences in other blood parameters compared to the control group. Moreover, injected pituitary DNA in chicken embryos was capable of increasing not only body weight but also the hyperplastic and proliferative changes in the reticuloendothelial elements in various organs particularly in the bursa of Fabricius and spleen.
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The experiment was conducted as an attempt to introduce DNA of pituitary glands either from broiler chicks (males or females) or turkey at market age into eggs of Montazah chickens (embryo cells) at the third day of incubation. Several hematological and biochemical parameters as well as histopathological changes in different organs were studied on the hatched chicks at different ages. The results showed that the introduction of foreign DNA had different expression of protein and lipid synthesis. The DNA injected chicks had the highest globulin concentrations (P<0.05), while it had insignificant differences in other blood parameters compared to the control group. Moreover, injected pituitary DNA in chicken embryos was capable of increasing not only body weight but also the hyperplastic and proliferative changes in the reticuloendothelial elements in various organs particularly in the bursa of Fabricius and spleen.

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