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Vitamin E and ascorbic acid efficacy on renal ischemia- reperfusion injury in experimental dogs [electronic resource].

By:

Mosbah, E

Contributor(s):

Nasr El-Deen, N. A. M

Language: English Summary language: Arabic Description: p.225-238Other title:

كفاءة فيتامين ه وحمض الأسكوربيك فى مجابهة الضرر الناجم عن اندفاع الدم للكلى بعد الاسكيمية فى كلاب التجارب.‪ [Added title page title]

Uniform titles:

Veterinary medical journal, 2008 v.56 (3) [electronic resource].

Subject(s):

Online resources:

Full Text Article

In: Veterinary Medical Journal 2008.v.56(3)Summary: It was reported that ischemia-reperfusion injury (IRI) is a major cause of acute renal damage in both the native and transplanted kidneys. Sixteen clinically healthy male dogs were exposed to 45 minutes renal ischemia followed by reperfusion and unilateral nephrectomy. Those dogs were subdivided equally into 4 groups. Gp.(l) was the positive control, gp.(2) was treated with vitamin E (20mg / kg Bwt/ day), gp.(3) was treated with ascorbic acid (30mg / mg / kg Bwt/ day) and gpo (4)was treated with both drugs. The experimental dogs were sacrificed, 7day after surgery. Specimens were taken from the left kidney in all groups.

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It was reported that ischemia-reperfusion injury (IRI) is a major cause of acute renal damage in both the native and transplanted kidneys. Sixteen clinically healthy male dogs were exposed to 45 minutes renal ischemia followed by reperfusion and unilateral nephrectomy. Those dogs were subdivided equally into 4 groups. Gp.(l) was the positive control, gp.(2) was treated with vitamin E (20mg / kg Bwt/ day), gp.(3) was treated with ascorbic acid (30mg / mg / kg Bwt/ day) and gpo (4)was treated with both drugs. The experimental dogs were sacrificed, 7day after surgery. Specimens were taken from the left kidney in all groups.

Summary in arabic.

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