Haematotoxic and biochemical hazards induced by long-termexposure of female nile tilapia (Oreochromis niloticus) to carbofuran [electronic resource].

Includes references.

The present study was carried out to measure the influences of sublethal toxicity of carbofuran (carbamate), which is one of the most commonly used nematicides, on the reproductive performance of Oreochromis niloticus. The 96 hr LC₅₀ of the carbofuran was determined for the adult Nile tilapia and it was 3.04 pglml. The present experimental assay was evaluated on the 60th day of exposure to 1/50, 1/25 and 1/10 LC₅₀ of the pesticide in comparison with control fish group. The induced hazard effects were obvious in blood parameters as well as blood chemistry. The insignificant decrease of the erythrocytes count (RBCs), haemoglobin content (Hb) and hematocrit value (Hct) were dose depended. The plasma glucose level of the treated fish was significantly increased (hyperglycaemia) in response to dose dependent of carbofuran exposure. Nonetheless, the total plasma lipid (highly significant) and total plasma protein (significantly lowered) under the effect of intoxication with the pesticide. The plasma Aspartate amino-transferase (AST) and Alanine amino-transferase (ALT) enzymes activities were elevated significantly in fish exposed to carbofuran. Also the plasma urea (highly significant) and creatinine (insignificant) were increased in toxicated fish in comparison with those of control specimens.

Summary in Arabic.

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