Antibacterial and immunological evaluation of gentamicin and spectinomycin in chickens [electronic resource].

Includes references.

Two hundreds and ten one day old hubbard chicks were used in this study. They were divided into 6 groups.• The first group was kept as control. The second group was experimentally infected with 0.2 ml of broth containing 10-8 C.F.U. of S.pullorum given orally and left as positive control. The third group was experimentally infected orally with S.pullorum and intramuscularly injected with gentamicin; 5 mg/kg b.wt.for 5 successive days. The fourth group was experimentally infected with S.pullorum and injected I/ M with spectinomycin 20 mg/kg b. wt. twice with one day apart. The fifth group was injected I/M with gentamicin in the same dose regimen, while sixth group was I/M treated with spectinomycin 20 mg/kg b.wt. twice with one day apart. Non infected and gentamicin treated birds demonstrated significant decrease in total proteins. Infected non treated birds showed a significant increase in the total leucocytic count and serum total proteins. While treatment of infected birds with spectiomycin elicited a signifiCant decrease in total leucocytic count.

Summary in Arabic.

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